Amino sugars are components of all body tissues including those which holds cells together. NAG forms cartilage, ligaments and tendons forming an important substrate in the connective tissues lining the intestinal tract and musculoskeletal system.
Additional Information
N.A.G. is a key component of synovial and bursal fluid, and connective tissue
N.A.G. is required by the tendons and ligaments and is rich in chondroitins
N.A.G. is a component of the gel-like matrix between collagen fibres
N.A.G. helps support the immune system and is a component of some essential enzymes
N.A.G. is a component of mucous membranes lining the digestive, respiratory and urinary tracts
N.A.G. encourages the growth of beneficial bacteria in the gastrointestinal tract
Suitable for children and the elderly
Benefits
Preliminary research suggests that N-acetylglucosamine may offer certain health benefits. Here's look at several key findings from the available studies:
Osteoarthritis: N-acetyl glucosamine may help reduce the inflammation associated with osteoarthritis, suggests a preliminary study published in Annals of the Rheumatic Diseases in 2005. In tests on rabbits, scientists determined that N-acetylglucosamine helped alleviate arthritis-related inflammation and inhibit the breakdown of cartilage.
Inflammatory Bowel Disease: N-acetylglucosamine shows promise in the treatment of inflammatory bowel disease (a class of conditions that includes Crohn's disease and colitis), according to a pilot study published in Alimentary Pharmacology and Therapeutics in 2000. In tests on 10 children with severe Crohn's disease and two children with severe ulcerative colitis, researchers found that daily treatment with N-acetylglucosamine led to a significant improvement in symptoms and a decrease in inflammation.
Multiple Sclerosis: A 2011 study from the Journal of Biological Chemistry indicates that N-acetylglucosamine may help suppress the destructive autoimmune response involved in multiple sclerosis. In tests on mice, researchers demonstrated that N-acetylglucosamine may help inhibit the growth and function of abnormal cells that, in multiple sclerosis patients, prompt the immune system to break down central nervous system tissue involved in insulating nerves.
Skin Lightening: N-acetyl glucosamine may help promote lightening of the skin when used as an ingredient in skincare products, according to a 2007 study published in the Journal of Cosmetic Dermatology. In an eight-week-long clinical trial, the study's authors found that use of N-acetyl glucosamine helped reduce abnormal darkening of the skin. The study also found that N-acetyl glucosamine may be especially effective for skin-whitening when used in combination with niacinamide (a form of vitamin B sometimes used in skincare products).